Click on the Practice Question to view the synthesis of the literature and the practice guidance or recommendation.
Q: What are the energy and protein requirements of non-obese (i.e. healthy weight or underweight) critically ill adults?
Q: What are the energy and protein requirements of obese critically ill adults?
Q: Is permissive underfeeding (hypocaloric feeding) or an initial strategy of trophic (low dose) feeding associated with improved outcomes in critically ill adults compared to feeding according to calculated energy requirements?
Q: Does early enteral nutrition (initiating feeding within 48 hours of admission to ICU) versus delayed enteral nutrition (initiated within 48 to 96 hours of admission) result in improved outcomes in critically ill patients?
Q: Does continuous administration of enteral nutrition compared with intermittent or bolus feeding result in better outcomes in critically ill patients?
Q: Does enteral feeding into the small intestine (post-pyloric) compared to gastric feeding result in improved outcomes in critically ill patients?
Q: What strategies are effective to optimize delivery of enteral nutrition and minimize risks in critically ill patients (e.g. feeding protocols, motility agents, positioning)?
Q: Is the practice of measuring gastric residual volume (GRV) in mechanically ventilated critically ill patients who are tube fed into the stomach reliable for predicting tolerance, regurgitation and aspiration? What is considered an acceptable GRV?
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