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[B] The following conclusions are supported by fair evidence:
Observational studies suggest that obesity increases the risk for developing osteoarthritis (OA), therefore achieving or maintaining a healthy BMI is desirable to prevent OA. In overweight or obese individuals with knee OA, meta-analyses of randomized clinical trials has shown that a weight loss of >5% over a five-month period can result in modest improvements in pain and function, but does not impact disease progression. Based