Information in this section pertains to all global PEN® partners except where country flags are
visible. Click on the flag(s) for country-specific information. If a country flag is not listed, there is
no information specific to that country.
[A] The following conclusions are supported by good evidence:
There is good evidence to support the use of antiemetics in cancer treatment-related nausea and vomiting.
[B] The following conclusions are supported by fair evidence:
Prophylactic cryotherapy (i.e. sucking on ice chips starting five minutes before chemotherapy bolus is given and for a total of 20-30 minutes) while receiving certain chemotherapeutic agents (Melphalan or bolus 5-FU) may prevent the development of severe oral