Information in this section pertains to all global PEN® partners except where country flags are
visible. Click on the flag(s) for country-specific information. If a country flag is not listed, there is
no information specific to that country.
Disease Etiology
Exercise-induced anaphylaxis (EIA) has been defined as “the onset of allergic symptoms during, or immediately after, exercise, the clinical signs being various degrees of urticaria, angioedema, respiratory and gastrointestinal signs and even anaphylactic shock” (1). Sensitivity to a specific food as a predisposing factor of EIA has been defined as food-dependant EIA (FDEIA) (2). A number of foods are associated with FDEIA, but the most common food implicated worldwide is wheat