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[A] The following conclusions are supported by good evidence:It is common in sickle cell disease (SCD) for zinc status to be low. A Cochrane review of RCTs found that zinc supplementation (typically 50-150 mg/day of elemental zinc) was associated with improvements in serum zinc levels, number of sickle cell crises (vaso-occlusive pain crises), number of clinical infections and healing of leg ulcers among those with SCD.
[B] The following conclusions are supported by fair evidence:There is a