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[B] The following conclusions are supported by fair evidence:
Specific dosing recommendations for treating vitamin B12 deficiency vary. However, in general, the following is recommended by guidelines and supported by research trials:
- As outlined in Canadian guidelines, an oral dose of vitamin B12 ranging from 1000 to 2000 ug/day (not sustained release) is recommended for pernicious anemia and food-bound cobalamin malabsorption. Lower doses (such as 100-250 ug/day) are thought to be adequate in