Hepatic Disorders

Pathway Contributor: Diana Mager

Bio:
Diana Mager is a Pediatric Research Nutrition Fellow and the Home TPN dietitian within the Division of Gastroenterology, Hepatology and Nutrition at the Hospital for Sick Children in Toronto Canada. She is also the Clinical Educator within the Department of Clinical Dietetics at the Hospital for Sick Children. Diana completed her PhD in the Department of Nutritional Sciences at the University of Toronto in 2004 under the supervision of Dr. Paul Pencharz. Her doctoral work focused on branched chain amino acid metabolism in children with chronic liver disease. Her doctoral work focused on the dietary and metabolic characteristics of obese children with non-alcoholic fatty liver disease. Dr. Mager will be taking up a new joint position in Nutrition Services as a Program Leader in Research in Capital Health and as an Assistant Professor in the Department of Agriculture, Food and Nutritional Sciences at the University of Alberta in the summer of 2006.

Contributions:

• Are energy requirements altered in individuals with hepatitis B and C virus (HVB and HCV)?  

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• What is the optimal macronutrient composition of the diet for an individual with chronic hepatitis B and C?  

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• Is weight loss beneficial for overweight individuals diagnosed with non alcoholic fatty liver (NAFLD) disease?  

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• What is the optimal dietary composition for an individual with non-alcoholic fatty liver disease (NAFLD)?  

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• What is the optimal nutrient composition of the diet for an individual with alcoholic liver disease?  

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• What are the major fluid and electrolyte issues that occur in moderate to severe liver disease?  

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• Are there any benefits in supplementing with branched chain amino acids (BCAA) for individuals with chronic liver disease?  

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• Is fat-soluble vitamin supplementation necessary/safe for individuals with chronic liver disease?  

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• Is supplementation with water-soluble vitamin (s) necessary and safe for individuals with chronic liver disease?  

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• Is supplementation with minerals necessary/safe for individuals with chronic liver disease?  

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• What vitamin supplements are required during acute liver failure?  

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• Is there any evidence to support the use of milk thistle (silymarin) in chronic liver disease?  

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• Should individuals diagnosed with Wilson's disease avoid copper?  

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• Is there any evidence to support the use of herbal medicines to treat liver disease?  

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• Is there evidence to support protein restriction in end stage liver disease (e.g. encephalopathy) and if so to what extent should protein be restricted?  

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• How much protein does an individual with chronic liver disease need?  

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• Hepatic Disorders Background

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• Hepatic Disorders Background

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  Role: Reviewer